Wednesday, September 28, 2011

Fw: QC Past, Present and Future

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From: Westgard QC <westgard@westgard.com>
Sender: Westgard QC <westgard=westgard.com@mail49.us1.rsgsv.net>
Date: Wed, 28 Sep 2011 06:00:00 +0300
To: Antar Alomani<aomani@KSU.EDU.SA>
ReplyTo: Westgard QC <westgard@westgard.com>
Subject: QC Past, Present and Future

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QC Past, Present and Future

QC Reality Check, Part Five

Normalization of Deviance

Identifying Failure Modes
 


On the Blog

Error Rates at the POC

Error Rates in an Indian Clinical Laboratory

Rejection rates in 6 Thai Laboratories

Glucose meter vs. Lab result: What would you do?

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Couldn't attend the Westgard Workshops this year?









QC Past, Present and Future

At the 2011 AACC/ASCLS convention, the Bio-Rad industry workshop featured Dr. Westgard, who reviewed the history of quality control in laboratories, as well as its present problems and possible futures.

Where have we been, Where are we now, and Where are we going with QC?



QC Reality Check, Part Five

Dr. Dietmar Stockl continues his series on quality control. This article discusses the need for stability and its relationship to the quality requirement.

How stable should my laboratory test be?



Normalization of Deviance

Back in 1996, Diane Vaughan coined the term "Normalization of Deviance" to describe how NASA and its contractors rationalized their way into the disastrous decision to launch the Challenger space shuttle in 1986. Decades later, this safety concept still applies - and is very germane to our current QC practices in the laboratory.

Have deviations in testing and QC become too normal?



Risk Analysis: Identifying Failure Modes

An essential part of Risk Analysis is figuring What Can Go Wrong - in other words, the failure modes of a process. So you've assembled your team, chosen your process, diagrammed the process - now what? Here's a guide to identifying failure modes and graphically summarizing them in a fishbone diagram.
[book excerpt/preview]

What are my risks in laboratory testing processes?



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Sunday, September 25, 2011

Fw: AMEDEO Nutrition 26.09.2011 - AID:196261

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-----Original Message-----
From: "Sebastian.Kamps@amedeo.com" <Sebastian.Kamps@amedeo.com>
Date: Sat, 24 Sep 2011 21:43:16
To: Antar Alomani<aomani@KSU.EDU.SA>
Subject: AMEDEO Nutrition 26.09.2011 - AID:196261


1. AMEDEO Nutrition
http://www.amedeo.com

2011-09-26

Your Personal Amedeo Web Page:
http://amedeo.com/summary/px.php?table=nut&cid=196261


2. Full-Text Article

Frey O, Bruns L, Morawietz L, Dunussi-Joannopoulos K, Kamradt T.
B cell depletion reduces the number of autoreactive T helper cells and prevents glucose-6-phosphate isomerase-induced arthritis.
PLoS One. 2011;6(9):e24718.
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0024718


Best regards,

Bernd Sebastian Kamps
www.linkedin.com/in/bskamps


________________ ** New articles **_________________


1. LEICHTLE AB, Helmschrodt C, Ceglarek U, Shai I, et al.
Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in
moderately obese men.
Am J Clin Nutr. 2011.
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ABSTRACT available


2. FAIRWEATHER-TAIT SJ, Skinner J, Guile GR, Cassidy A, et al.
Diet and bone mineral density study in postmenopausal women from the TwinsUK
registry shows a negative association with a traditional English dietary pattern
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Am J Clin Nutr. 2011.
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ABSTRACT available


3. RADHIKA MS, Nair KM, Hari Kumar R, Vishnuvardhana Rao M, et al.
Micronized ferric pyrophosphate supplied through extruded rice kernels improves
body iron stores in children: a double-blind, randomized, placebo-controlled
midday meal feeding trial in Indian schoolchildren.
Am J Clin Nutr. 2011.
http://amedeo.com/p2.php?id=21940595&s=nut&pm=7e2b9c50b84c0ee
ABSTRACT available


4. CHAPUT JP.
Do active video games increase food intake?
Am J Clin Nutr. 2011;94:1155.
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Waste and hydrogenation lower omega-3 and omega-6 fat intake estimates for
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Am J Clin Nutr. 2011;94:1152-3.
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6. OKUBO H, Miyake Y, Sasaki S, Tanaka K, et al.
Maternal dietary patterns in pregnancy and fetal growth in Japan: the Osaka
Maternal and Child Health Study.
Br J Nutr. 2011.
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ABSTRACT available


7. BUCHER T, van der Horst K, Siegrist M.
The fake food buffet - a new method in nutrition behaviour research.
Br J Nutr. 2011.
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ABSTRACT available


8. KASBI CHADLI F, Andre A, Prieur X, Loirand G, et al.
n-3 PUFA prevent metabolic disturbances associated with obesity and improve
endothelial function in golden Syrian hamsters fed with a high-fat diet.
Br J Nutr. 2011.
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ABSTRACT available


9. ALLEVA R, Di Donato F, Strafella E, Staffolani S, et al.
Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
Br J Nutr. 2011.
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ABSTRACT available


10. FLATTUM C, Friend S, Story M, Neumark-Sztainer D, et al.
Evaluation of an individualized counseling approach as part of a multicomponent
school-based program to prevent weight-related problems among adolescent girls.
J Am Diet Assoc. 2011;111:1218-23.
http://amedeo.com/p2.php?id=21802570&s=nut&pm=7e2b9c50b84c0ee
ABSTRACT available


11. STEIN K.
The balancing act of diversity initiatives.
J Am Diet Assoc. 2011;111:1110-7.
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13. LOURENCO AP, Vasques-Novoa F, Fontoura D, Bras-Silva C, et al.
A Western-Type Diet Attenuates Pulmonary Hypertension with Heart Failure and
Cardiac Cachexia in Rats.
J Nutr. 2011.
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ABSTRACT available


14. MARGOLIS KL, Wei F, de Boer IH, Howard BV, et al.
A Diet High in Low-Fat Dairy Products Lowers Diabetes Risk in Postmenopausal
Women.
J Nutr. 2011.
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ABSTRACT available


15. MORI T, Kondo H, Hase T, Murase T, et al.
Dietary Phospholipids Ameliorate Fructose-Induced Hepatic Lipid and Metabolic
Abnormalities in Rats.
J Nutr. 2011.
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ABSTRACT available


16. PARK SH, Kim JL, Lee ES, Han SY, et al.
Dietary Ellagic Acid Attenuates Oxidized LDL Uptake and Stimulates Cholesterol
Efflux in Murine Macrophages.
J Nutr. 2011.
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ABSTRACT available


17. OKAZAKI Y, Tomotake H, Tsujimoto K, Sasaki M, et al.
Consumption of a Resistant Protein, Sericin, Elevates Fecal Immunoglobulin A,
Mucins, and Cecal Organic Acids in Rats Fed a High-Fat Diet.
J Nutr. 2011.
http://amedeo.com/p2.php?id=21940508&s=nut&pm=7e2b9c50b84c0ee
ABSTRACT available


_____________________ ** End **______________________



We have screened the following journals for you:
AIDS
Am J Clin Nutr
Br J Nutr
J Am Diet Assoc
J Nutr
JAMA
Lancet
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Tuesday, September 20, 2011

FW: September 2011: Untangling the knot of mitochondrial disease

 
 

From: CAP Today [CAP_Today.UM.A.1.19304@list-is.cap.org]
Sent: 19 September 2011 14:47
To: Antar Alomani
Subject: September 2011: Untangling the knot of mitochondrial disease



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September 2011 digital edition September 19, 2011

In this issue
Decades on, IHC keeps making its mark
AP labs seek to sync with
growing IT menu
Directing a lab: sink, swim—
or look to CAP course
From the President's Desk:
Survival skills for small practices
Eyes on the prize improves
AP specimen processing
Lab automation—
total tube management and more
Product guide: Laboratory
automation systems and workcells
Full automation as solution—
U of Iowa's story
Checklists now slimmer,
simpler, ROAD-mapped
How to prepare for an interview,
size up an offer
Pharmacogenomics and more
at AACC 2011
Clinical Pathology Abstracts
Anatomic Pathology Abstracts
Q & A
Newsbytes
Marketplace
People
Put it on the Board
Classified Advertising
New online, interactive version of product guides
Compare and contrast lab instruments and software feature by feature using the new online, interactive version of CAP TODAY's renowned product guides.
Laboratory automation systems
and workcells
In vitro blood gas analyzers
Automated molecular platforms
Chemistry analyzers for mid-
and high-volume laboratories
Positive patient identification products
Automated immunoassay analyzers
Coagulation analyzers—point of care, self-monitoring
Billing/accounts receivable systems
Laboratory-provider links software
Bedside glucose testing systems
Middleware systems
Anatomic pathology computer systems
Coagulation analyzers
Hematology analyzers
Laboratory information systems
Chemistry analyzers for
low-volume laboratories
Blood bank information systems

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Untangling the knot of
mitochondrial disease
Karen Titus

Experts in mitochondrial disease are a persevering lot. Like Tristan and Isolde filling their lungs for Act 2, they're in it for the long haul.

"It's a field I've been in for 35 years," says Michael J. Bennett, PhD, professor of pathology and laboratory medicine, Perelman School of Medicine at the University of Pennsylvania, and director, Metabolic Disease Laboratory, Children's Hospital of Philadelphia. "And we're all still learning, basically."

"It's a difficult field," agrees Brian Robinson, PhD, director of the mitochondrial research laboratory, Hospital for Sick Children (SickKids), Toronto. "Even though I've been in it for 30 years, it's hard for me to figure out where it's headed."
Patients with mitochondrial disease generally search for years for a diagnosis, often consulting multiple specialists and undergoing numerous tests before the appropriate tests are performed, say Drs. Douglas Wallace (left) and Michael Bennett. "People ought to be aware that it's a possibility from a clinical perspective," Dr. Bennett says, "not something you suddenly realize you haven't done at the end."
"I've been at this now for 40 years," says Douglas C. Wallace, PhD, the Michael and Charles Barnett Chair of Pediatric Mitochondrial Medicine and Metabolic Disease, and director, Center for Mitochondrial and Epigenomic Medicine, CHOP. "When I started, nobody thought that studying mitochondrial DNA would be of any interest clinically." Only in recent years has medicine done an about-face on the matter, says Dr. Wallace, who likes to talk about the need to upend 150 years of Mendelian genetics in order to arrive at a proper diagnosis of mitochondrial disease.

If those are the experts talking, what are the prospects for physicians whose outlooks are less mitochondrial-centric?

The pace may be about to pick up, actually. While there's nothing easy about understanding and diagnosing mitochondrial disease—especially in children—breakthroughs appear imminent and could put laboratories in the thick of mitochondrial diagnostics. "These diseases are extraordinarily common, not rare," says Dr. Wallace, who is also professor, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania. (A common estimate is one in 4,000 or 5,000 lifetime risk, though others, including those interviewed for this article, suggest the risk may be one in 2,000, or even less, for children.) "So the need for this testing is going to be great in almost every path lab." [more]

Leica Microsystems

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